Monitoring of the Parasite Load in the Digestive Tract of Rhodnius prolixus by Combined qPCR Analysis and Imaging Techniques Provides New Insights into the Trypanosome Life Cycle.

Here we report the monitoring of the digestive tract colonization of Rhodnius prolixus by Trypanosoma cruzi using an accurate determination of the parasite load by qPCR coupled with fluorescence and bioluminescence imaging (BLI).These complementary methods revealed critical steps necessary for the parasite population to colonize the insect gut and

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Ecological niche of plant pathogens

Disease ecology is a new approach to the understanding of the spread and dynamics of pathogens in natural and man-made environments.Defining and describing the ecological niche of the pathogens is one of the major tasks for ecological theory, as well as for practitioners preoccupied with the control and forecasting of established and emerging disea

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WD40 domain divergence is important for functional differences between the fission yeast Tup11 and Tup12 co-repressor proteins.

We have previously demonstrated that subsets of Ssn6/Tup target genes have distinct requirements for the Schizosaccharomyces pombe click here homologs of the Tup1/Groucho/TLE co-repressor proteins, Tup11 and Tup12.The very high level of divergence in the histone interacting repression domains of the two proteins suggested that determinants distingu

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Digital Mental Health Interventions for Alleviating Depression and Anxiety During Psychotherapy Waiting Lists: Systematic Review

BackgroundDepression and anxiety have become increasingly prevalent across the globe.The rising need for treatment and the lack of clinicians has resulted in prolonged waiting times for patients to receive their first session.Responding to this gap, digital mental health interventions (DMHIs) have been found effective in treating depression and anx

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